Huellas dactilares y perfiles de metabolitos: Experimentos de RMN y análisis multivariado

Autores/as

Dra. Norma Santos
Universidad Tecnológica de la Mixteca
Dra. Beatriz
Universidad Tecnológica de la Mixteca
Raúl Salas Coronado
+529535320214 Ext 400
https://orcid.org/0000-0002-5458-0157

Palabras clave:

Huellas dactilares, Perfiles de metabolitos, Análisis multivariante, Análisis de componentes principales

Sinopsis

La espectroscopía de RMN es una técnica poderosa para el estudio de propiedades y composición de alimentos y plantas. Las propiedades pueden estudiarse a través de experimentos de RMN en el dominio del tiempo. Mientras que el estudio de la composición y cuantificación de metabolitos se puede llevar a cabo a partir experimentos de RMN en el dominio de la frecuencia. Esto se puede lograr a partir de dos enfoques generales. El primero consiste en adquirir las huellas dactilares de metabolitos a partir de un análisis multivariante de datos de RMN en 1D y 2D ya sea en el dominio del tiempo o frecuencia. La adquisición de huellas dactilares por RMN suele ser una herramienta rápida y eficaz para discriminar entre grupos de muestras relacionadas a partir de la identificación de las regiones espectrales más distintivas. Un segundo enfoque consiste en realizar perfiles de metabolitos con los espectros de RMN, principalmente de 1H, a partir de extractos de muestras. Esto normalmente permite identificar alrededor de 40 metabolitos en un extracto sin fraccionar. Los perfiles también se utilizan para realizar tanto análisis cualitativos como cuantitativos para comparar grupos de muestras. Los perfiles de metabolitos permiten explorar los orígenes de la variabilidad entre los grupos de muestras estudiadas. Los dos enfoques conjuntamente generan el fenotipo metabólico de una planta. En el presente capítulo se describen las técnicas más representativas para la obtención de huellas dactilares en el dominio del tiempo y la frecuencia, y los métodos de procesado de espectros para la generación de perfiles metabólicos. Así como la descripción del análisis de componentes principales, uno de los métodos de análisis multivariante más empleado para el estudio de perfiles metabólicos en RMN incluyendo el procesamiento previo de los datos espectrales.

Capítulos

  • Huellas dactilares y perfiles de metabolitos: Experimentos de RMN y análisis multivariado
    Norma Francenia Santos Sánchez, Beatriz Hernández Carlos, Raúl Salas Coronado

Biografía del autor/a

Raúl Salas Coronado, +529535320214 Ext 400

Raul Salas Coronado es Ingeniero Quimico y Doctor en Ciencias Químicas. Desde septiembre del 2003 es Profesor-Investigador adscrito al Instituto de Agroindustrias de la Universidad Tecnológica de la Mixteca (UTM). Sus investigaciones están relacionadas con el estudio de productos naturales en plantas y alimentos; y la evaluación del efecto del procesado térmico sobre la composición de pigmentos y antioxidantes en alimentos. 

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Publicado

April 13, 2022
Derechos de autor 2022 Imprenta de libros de la Universidad Tecnológica de la Mixteca