UNA APROXIMACIÓN A LA ESPECTROSCOPÍA DE RESONANCIA MAGNÉTICA NUCLEAR
Palabras clave:
Fundamentos teóricos de RMN, RMN de líquidos, RMN uni- y bidimensional, Metabolómica, RMN de materiales, RMN de alimentos, RMN dinámica, RMN de productos naturalesSinopsis
Una aproximación a la espectroscopía de Resonancia Magnética Nuclear (RMN) fue concebida como un primer libro realizado por la Universidad Tecnológica de la Mixteca en colaboración con la Sociedad Mexicana de Resonancia Magnética Nuclear AC.
Cabe destacar la valiosa colaboración de los revisores que de manera objetiva y rigurosa enriquecieron cada uno de los capítulos.
La Resonancia Magnética Nuclear (RMN) es el método espectroscópico con mayor innovación tanto en aspectos experimentales como en sus aplicaciones. Motivados en estos aspectos se planteó realizar un libro en el que se encontraran desde los aspectos básicos de la RMN hasta algunas de sus aplicaciones más importantes y recientes como son el estudio metabólico.
La emergencia sanitaria provocada por la pandemia del virus SARS-Cov-2, motivó la realización de eventos a distancia. Por primera vez organizamos gracias al apoyo de CONACYT, de los patrocinadores y la excelente organización del comité organizador de la Universidad Tecnológica de la Mixteca, la 6ª Reunión de RMN Experimental en la modalidad virtual. En este libro se encuentran recopiladas las contribuciones presentadas en carteles como flash.
Cada uno de los capítulos fue realizado gracias a la experiencia de profesores y estudiantes de posgrado de la Universidad Autónoma Metropolitana-Xochimilco, Universidad Nacional Autónoma de México, Centro de Investigación y de Estudios Avanzados, Universidad del Papaloapan, Universidad Tecnológica de la Mixteca, Universidad Autónoma de Nuevo León e Imperial College London.
En el presente libro se describe de manera simple y con rigor académico los fundamentos de la RMN, los experimentos más útiles para la asignación de compuestos en una y dos dimensiones, se explica la manera de asignar y elucidar compuestos basados en la evidencia experimental de esta espectroscopia, de manera general se muestran los métodos que permiten demostrar y cuantificar la dinámica de los compuestos químicos, se llama la atención sobre la oportunidad de utilizar espectrómetros de RMN con imanes que no requieren criogénicos, se describen algunas aplicaciones en la determinación del reconocimiento molecular. La última parte del libro está dedicada a la contribución del uso de la RMN en la metabolómica desde la descripción de las herramientas necesarias para realizarla hasta algunos estudios prácticos aplicados al estudio del perfil metabolómico humano.
Dr. Armando Ariza Castolo
Investigador del Departamento de Química
Centro de Investigación y Estudios Avanzados
Ciudad de México, México
Capítulos
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Capítulo 1. Principios básicos de RMNEspañol
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Capítulo 2. Experimentos de RMN en una y dos dimensionesEspañol
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Capítulo 3. Elucidación y asignación de estructura por RMNEspañol
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Capítulo 4. Relajación, la clave para determinar la dinámica molecular: RMN dinámica
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Capítulo 5. RMN libre de criogénicosEspañol
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Capítulo 6. La RMN una herramienta en el reconocimiento molecular de aniones
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Capítulo 7. Huellas dactilares y perfiles de metabolitos: Experimentos de RMN y análisis multivariadoEspañol
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Capítulo 8. La RMN en el estudio del metaboloma humano: Definiciones y aspectos prácticosEspañol
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Capítulo 9. Estudios del perfil metabolómico por RMNEspañol
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Capítulo 10. Memorias de la 6ª Reunión de RMN: CartelesEspañol
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Capítulo 11. Memorias de la 6ª Reunión de RMN: Resúmenes de conferenciasEspañol
Citas
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Jacyna, Julia, Ma
